For the studies described here, it was found that the study population consisted of men and women aged 18 to 80 years. They were instructed to start treatment with tramadol in controlled and prolonged release tablets in a single daily dose of 150 mg or 200 mg. Some explanations of the researchers regarding certain precautions that are important when the patient takes tramadol should be taken into account. These reported aspects are patients who have been excluded from the study due to: tramadol hypersensitivity, severe respiratory failure, severe liver or kidney failure, drug or alcohol dependence, pregnant women, patients with severe psychiatric or cognitive impairment, patients treated previous.
As part of the study, it should be noted that after initiation of treatment, each patient was observed after a week and once a month. The results have been carefully evaluated for different variables. A total of 907 patients participated in the study, including a higher proportion of women. The majority of patients (93.84%) started treatment with 150 mg of tramadol with prolonged and controlled release. The remaining percentage did so with 200 mg of tramadol from https://tramadolguru.com/. Some of the general data that the researchers observed indicated that women showed a much higher intensity of pain than men. According to this feature, the elderly were also more physically involved in pain.
The results evaluated by the researchers showed that this tramadol formula proves effective in reducing chronic non-oncology pain from the first week in which it is administered. In addition, tramadol was found to have also contributed to improving the quality of sleep, as well as to its own interruption due to pain. On the other hand, the tolerance of treatment was good, with minor side effects and short duration. The most common side effects were nausea and vomiting. According to the researchers, the adverse effects that occur at the beginning decrease with the progress of treatment. In this sense, the most persistent symptoms were manifestations of the autonomic nervous system, dry mouth and sweating, as well as constipation.